We research viruses. From Mpox to Ebola, to respiratory diseases such as RSV and Influenza, we seek better understanding to drive better therapies.
We Are an Integrated Virology Laboratory
Our mission is to advance virology research, fostering innovation and collaboration within the scientific community. Within this mission we apply big data analysis, genomics, biochemistry, and molecular biology to understand how viruses function and how infected organisms respond to infection. Our continuing mission is to find ways to reduce suffering from diseases inflicted through virus infection.
Ongoing Research Projects
Below are some of the ongoing research projects in the laboratory. The laboratory maintains broad research portfolio, so current projects may differ from what is highlighted below. Visit a more detailed description by clicking here
Viral Genomic Epidemiology
Tracking Genetic Change As Viruses Are Transmitted From Person to Person
We are actively engaged in whole virus genome sequencing. Our efforts illuminate how viruses like RSV, influenza, and SARS-CoV-2 are changing as they circulate in humans. This helps uncover unexpected changes that can predict future outbreaks and highlight transmission scenarios that help us understand how to control virus spread.
Small molecules that block virus replication
Identifying/Developing New Antiviral Small Molecules
We have a longstanding interest in finding new antiviral small molecules that block virus replication. This has taken the form of screening for new small molecules, identifying high-quality candidates and then work with chemists to develop drug-like molecules. One ongoing project is focused on small molecule inhibitors of Mpox and other members of the orthopoxvirus family.
Molecular virology and virus evolution
Creating Tool Viruses
For many projects, we create rationally developed, attenuated viruses. Our approaches are aimed at finding improved vaccine candidates and understanding the evolutionary forces that shape the virus genome.
Sasha Behar
Research Technician
John Connor
Lab Director
Michelle Nguyen
Graduate Student
Dr. Emily LaVerriere
Postdoctoral Fellow